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Class Ia Phosphatidylinositol 3-Kinase

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Definition: A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the heterodimerization of a p110 catalytic and a p85, p55, or p50 regulatory subunit. This subclass of enzymes is a downstream target of TYROSINE KINASE RECEPTORS and G PROTEIN-COUPLED RECEPTORS.      Other names Phosphoinositide-3-Kinase, Regulatory Subunit 2; Phosphoinositide-3-Kinase, Regulatory Subunit 1; Phosphoinositide-3-Kinase, Catalytic, delta Polype; Phosphoinositide-3-Kinase, Catalytic, beta Polypep; Phosphoinositide-3-Kinase, Catalytic, alpha Polype; Phosphatidylinositol 3-Kinase, Class Ia; Class Ia Phosphatidylinositol 3-kinase, Regulatory; Class Ia Phosphatidylinositol 3-kinase, Regulatory; Class Ia Phosphatidylinositol 3-kinase, Regulatory; Class Ia Phosphatidylinositol 3-Kinase, p85beta Su; Class Ia Phosphatidylinositol 3-Kinase, p85alpha S; Class Ia Phosphatidylinositol 3-Kinase, p55gamma S; Class Ia Phosphatidylinositol 3-Kinase, p55alpha S; Class Ia Phosphatidylinositol 3-Kinase, p50alpha S; Class Ia Phosphatidylinositol 3-Kinase, p110delta ; Class Ia Phosphatidylinositol 3-Kinase, p110beta S; Class Ia Phosphatidylinositol 3-Kinase, p110alpha ; p85beta Subunit, Class Ia Phosphatidylinositol 3 K; p85alpha Subunit, Class Ia Phosphatidylinositol 3 ; p55gamma Subunit, Class Ia Phosphatidylinositol 3

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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