Definition: A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).
Other names Sialyl Apolipoprotein C III; Sialyl Apo C III; Apolipoprotein C-III, Sialyl; Apolipoprotein C III 1; Apolipoprotein C III 0; Apolipoprotein C III; ApoC III; Apo C-III, Sialyl; Apo C III 2; Sialyl Apolipoprotein C-III; Sialyl Apo C-III; Apo C III; Apolipoprotein CIII; Apolipoprotein C-III-1; Apolipoprotein C-III-0; ApoC-III; Apo C-III-2; Apo C-III
