Definition: CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. They inhibit the immune response by influencing the activity of other cell types. Regulatory T-cells include naturally occurring CD4+CD25+ cells, IL-10 secreting Tr1 cells, and Th3 cells.
Other names Treg Cell; Tr1 Cell; Th3 Cell; T-Lymphocyte, Regulatory; T-Cells, Naturally-Occurring Suppressor; T-Cell, Naturally-Occurring Suppressor; T Lymphocytes, Regulatory; T Cells, Regulatory; Suppressor T-Lymphocyte, Naturally-Occurring; Suppressor T-Cell, Naturally-Occurring; Suppressor T Lymphocytes, Naturally Occurring; Suppressor T Cells, Naturally Occurring; Regulatory T-Lymphocyte; Regulatory T Lymphocytes; Regulatory T Cells; Naturally-Occurring Suppressor T-Lymphocytes; Naturally-Occurring Suppressor T-Lymphocyte; Naturally-Occurring Suppressor T-Cells; Naturally-Occurring Suppressor T-Cell; Cells, Treg