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Sphingolipid Activator Proteins
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Definition
: A family of glycoprotein cofactors that are required for the efficient catabolization of SPHINGOLIPIDS by specific acid hydrolases such as GLUCOSYLCERAMIDASE; GALACTOCEREBROSIDASE; BETA-N-ACETYLHEXOSAMINIDASE; and CEREBROSIDE-SULFATASE.
Examples
G(M2) Activator Protein
;
Saposins
Other names
Hexosaminidase Activating Factor; Hexosaminidase A Activating Protein; Ganglioside Hydrolysis Activator Proteins; Ganglioside Degradation Activator Protein; GM1 Activator Protein; G(M1) Ganglioside Activating Factor; Cerebroside Sulfate Activator Protein; G(M1) Activator Protein