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Platelet Membrane Glycoprotein IIb

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Definition: Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN BETA3 to form PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX. It is synthesized as a single polypeptide chain which is then postranslationally cleaved and processed into two disulfide-linked subunits of approximately 18 and 110 kDa in size.     
See Also Platelet Glycoprotein GPIIb-IIIa Complex
Other names GP IIb; alphaIIb, Integrin; Surface Antigen, HUPL-ml; HUPL ml Surface Antigen; Glycoprotein IIb, Membrane; Antigen, HUPL-ml Surface; Antigen, CD41; Plasma Membrane Glycoprotein IIb; Membrane Glycoprotein IIb; Integrin alpha IIb; HUPL-ml Surface Antigen; GPalpha IIb; CD41 Cell Surface Antigen; CD41 Antigen; Integrin alphaIIb; CD41 Antigens; Antigens, CD41

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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