Definition: This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.
Other names beta4 Integrin, alpha6; alpha6beta4, Integrin; Tumor Specific Protein 180 Complex; Integrin, alpha6 beta4; Antigen, A9; alpha6 beta4 Integrin; alpha(6)beta(4) Integrin; alpha(6)beta(4) Epithelial Integrin; Tumor Specific Protein-180 Complex; TSP-180; Laminin-5 Receptor (alpha6beta4 Integrin); Integrin alpha(6),beta(4); A9 Antigen
