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Long-Term Synaptic Depression

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Definition: A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.  note category: do not confuse with clinical DEPRESSION or DEPRESSIVE DISORDERS    Other names Synaptic Depression, Long-Term; Physiological Long-Term Depressions; Physiological Long-Term Depression; Physiologic Long-Term Depression; Neurophysiological Long-Term Depressions; Neurophysiological Long-Term Depression; Neurophysiologic Long-Term Depression; Long-Term Depressions, Physiological; Long-Term Depressions, Neurophysiological; Long Term Depression, Physiological; Long Term Depression, Physiologic; Long Term Depression, Neurophysiological; Long Term Synaptic Depression; Long Term Depression, Neurophysiologic; Depressions, Physiological Long-Term; Depressions, Neurophysiological Long-Term; Depression, Physiological Long-Term; Depression, Neurophysiological Long-Term; Depression, Homosynaptic; Long-Term Depression, Physiological

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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