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Heymann Nephritis Antigenic Complex

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Definition: A complex of antigenic proteins obtained from the brush border of kidney tubules. It contains two principal components LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2 and LDL-RECEPTOR RELATED PROTEIN-ASSOCIATED PROTEIN. The name of this complex is derived from researcher, Dr. Walter Heymann, who developed an experimental model of membranous glomerulonephritis (GLOMERULONEPHRITIS) by injecting this antigenic complex into rats to induce an autoimmune response.  HEYMANN NEPHRITIS ANTIGEN GP330 see LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2 is also available   
See Also Glomerulonephritis
Examples Low Density Lipoprotein Receptor-Related Protein-2; LDL-Receptor Related Protein-Associated Protein 		Other names Receptor Associated Protein, Heymann Nephritis; Heymanns Antigen; Heymann Antigen; Heyman Nephritis Antigen; Receptor-Associated Protein, Heymann Nephritis; Nephritogenic Antigen; Heymann's Antigen; Fx1A Renal Tubular Antigen; Nephritis Antigen, Heyman

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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