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Guanine Nucleotide-Releasing Factor 2

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Definition: A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins.      Other names GRF 2; RAP1GRF1; GRF2 Protein, Mammalian; GRF-2; GRF2 Protein; GRF2; C3G Protein; Guanine Nucleotide Exchange Factor C3G

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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