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Hypokalemic Periodic Paralysis

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Definition: An autosomal dominant familial disorder characterized by recurrent episodes of skeletal muscle weakness associated with falls in serum potassium levels. The condition usually presents in the first or second decade of life with attacks of trunk and leg paresis during sleep or shortly after awakening. Symptoms may persist for hours to days and generally are precipitated by exercise or a meal high in carbohydrates. (Adams et al., Principles of Neurology, 6th ed, p1483)      Other names Periodic Paralysis- Hypokalemics; Periodic Paralysis, Hypokalemic; Periodic Paralysis Hypokalemic; Periodic Paralysis- Hypokalemic; Hypokalemic Periodic Paralysis, Familial; Primary Hypokalemic Periodic Paralysis; Paralysis, Hypokalemic Periodic; Familial Hypokalemic Periodic Paralysis

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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