encyclopedia of medical concepts
ψ 
ψ 
ψ 
ψ 

MPTP Poisoning

More information in Books or onNLM PubMed
Definition: A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)     
See Also 1-Methyl-4-phenylpyridinium 		Other names Poisoning, MPTP; Parkinsonism, MPTP-Induced; Neurotoxicity Syndromes, MPTP; MPTP Neurotoxicity Syndromes; MPTP Induced Parkinsonism; MPTP Induced Degeneration of the Striatum; Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyr; Neurotoxicity Syndrome, MPTP; MPTP-Induced Parkinsonism; MPTP-Induced Degeneration of the Striatum; MPTP Neurotoxicity Syndrome

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy