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Anticipation, Genetic

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Definition: The apparent tendency of certain diseases to appear at earlier AGE OF ONSET and with increasing severity in successive generations. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)     
See Also Genetic Predisposition to Disease; Penetrance; Trinucleotide Repeat Expansion
Other names Genetic Anticipations; Anticipations, Genetic; Genetic Anticipation

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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