Acquired Hyperostosis Syndrome (definition)

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ψ	Acquired Hyperostosis Syndrome

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Definition: Syndrome consisting of synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis (SAPHO). The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.

Other names Syndromes, SAPHO; Syndromes, Acquired Hyperostosis; Syndrome, SAPHO; Syndrome, Acquired Hyperostosis; SAPHO Syndromes; Hyperostosis Syndromes, Acquired; Hyperostosis Syndrome, Acquired; Acquired Hyperostosis Syndromes; Synovitis, Acne, Pustlosis, Hyperostosis, and Oste; SAPHO Syndrome

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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