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Interspersed Repetitive Sequences

More information in Books or onNLM PubMed
Definition: Copies of transposable elements interspersed throughout the genome, some of which are still active and often referred to as "jumping genes". There are two classes of interspersed repetitive elements. Class I elements (or RETROELEMENTS - such as retrotransposons, retroviruses, LONG INTERSPERSED NUCLEOTIDE ELEMENTS and SHORT INTERSPERSED NUCLEOTIDE ELEMENTS) transpose via reverse transcription of an RNA intermediate. Class II elements (or DNA TRANSPOSABLE ELEMENTS - such as transposons, Tn elements, insertion sequence elements and mobile gene cassettes of bacterial integrons) transpose directly from one site in the DNA to another.  GEN: prefer specifics - DNA TRANSPOSABLE ELEMENTS or RETROELEMENTS or its indentions   
See Also Mutagenesis, Insertional
Examples DNA Transposable Elements; Genomic Islands; Retroelements
Other names Sequences, Interspersed Repetitive; Sequences, Dispersed Repetitive; Sequence, Interspersed Repetitive; Sequence, Dispersed Repetitive; Repetitive Sequence, Interspersed; Repetitive Sequence, Dispersed; Repetitive Elements, Interspersed; Repetitive Element, Interspersed; Mobile Genetic Element; Jumping Gene; Interspersed Repetitive Sequence; Interspersed Repetitive Element; Genetic Element, Mobile; Gene, Jumping; Elements, Interspersed Repetitive; Element, Mobile Genetic; Element, Interspersed Repetitive; Dispersed Repetitive Sequence; Genetic Elements, Mobile; Elements, Mobile Genetic

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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