Definition: Transforming proteins encoded by erbB oncogenes from the avian erythroblastosis virus. The protein is a truncated form of the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) whose kinase domain is constitutively activated by deletion of the ligand-binding domain.
IM; coord with specific virus (IM); /drug eff /ultrastruct permitted; DF: note short X ref
Other names v erbB Proteins; Oncogene Proteins v erbB; Oncogene Products v erbB; Oncogene Proteins erbB; Oncogene Products v-erbB; v-erbB Proteins; erbB Oncogene Proteins
