Definition: Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
a 2d or more neopl of same or different histol type at same or different sites: do not confuse with NEOPLASMS, MULTIPLE PRIMARY (see note there); often follows ther (note X refs); IM; coord with each specific histol type (IM) & each precoord organ/neopl
See AlsoNeoplasms, Multiple Primary
Other names Treatment-Related Cancer; Treatment-Associated Neoplasms; Therapy-Related Cancer; Therapy-Associated Neoplasms; Second Primary Neoplasms; Second Neoplasm; Second Malignancy; Neoplasms, Treatment-Related; Neoplasms, Therapy-Related; Neoplasms, Metachronous Second Primary; Neoplasms, Metachronous; Treatment-Related Neoplasm; Treatment-Related Cancers; Treatment-Associated Neoplasm; Treatment-Associated Cancers; Treatment Related Neoplasms; Treatment Related Cancer; Treatment Associated Neoplasms; Treatment Associated Cancer; Therapy-Related Neoplasm
