Definition: Retrovirus-associated DNA sequences (mos) originally isolated from the Moloney murine sarcoma virus (Mo-MSV). The proto-oncogene mos (c-mos) codes for a protein which is a member of the serine kinase family. There is no evidence as yet that human c-mos can become transformed or has a role in human cancer. However, in mice, activation can occur when the retrovirus-like intracisternal A-particle inserts itself near the c-mos sequence. The human c-mos gene is located at 8q22 on the long arm of chromosome 8.
Other names v-mos Genes; mos Genes; c-mos Genes; v-mos Oncogene; v-mos Gene; v mos Oncogenes; v mos Genes; mos Proto-Oncogene; mos Proto Oncogenes; mos Oncogene; mos Gene; c-mos Proto-Oncogene; c-mos Gene; c mos Proto Oncogenes; c mos Genes; Proto-Oncogenes, mos; Proto-Oncogenes, c-mos; Proto-Oncogene, mos; Proto-Oncogene, c-mos; Oncogenes, v-mos