Genes (definition)

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ψ ψ	Genes, Retinoblastoma

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Definition: Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.

See Also Retinoblastoma

Other names Retinoblastoma Genes; Rb Genes; Genes, Rb; Retinoblastoma Gene; Rb Gene; Gene, Retinoblastoma; Gene, Rb

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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Genes, Retinoblastoma