Definition: Parts of the myosin molecule resulting from cleavage by proteolytic enzymes (PAPAIN; TRYPSIN; or CHYMOTRYPSIN) at well-localized regions. Study of these isolated fragments helps to delineate the functional roles of different parts of myosin. Two of the most common subfragments are myosin S-1 and myosin S-2. S-1 contains the heads of the heavy chains plus the light chains and S-2 contains part of the double-stranded, alpha-helical, heavy chain tail (myosin rod).
Other names Myosin S-2; Myosin S-1; Myosin Rod; Meromyosin Subfragments; Actomyosin Subfragments; Subfragments, Myosin; Subfragments, Meromyosin; Subfragments, Actomyosin; Subfragment-2, Myosin; Subfragment-2, Heavy Meromyosin; Subfragment-1, Myosin; Subfragment-1, Heavy Meromyosin; Myosin Subfragment 2; Myosin Subfragment 1; Myosin S 2; Myosin S 1; Meromyosin, Light; Meromyosin, Heavy; Meromyosin, Actoheavy; Meromyosin Subfragment-2, Heavy
