Definition: Mutant mice exhibiting a marked obesity coupled with overeating, hyperglycemia, hyperinsulinemia, marked insulin resistance, and infertility when in a homozygous state. They may be inbred or hybrid.
NIM when exper animal: no qualif; when IM, qualif permitted; do not forget also to check tag MICE; for X ref HYPERGLYCEMIC MICE do not add HYPERGLYCEMIA or OBESITY unless particularly discussed as diseases