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Defective Viruses

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Definition: Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus.  viruses lacking a complete genome & so unable to replicate completely or to form a protein coat   
Examples Hepatitis Delta Virus; Sarcoma Viruses, Feline; Sarcoma Viruses, Murine; Satellite Viruses; SSPE Virus 		Other names Incomplete Viruses; Defective Interfering Viruses; Defective Interfering Particles; Viruses, Incomplete; Viruses, Defective Interfering; Viruses, Defective; Virus, Incomplete; Virus, Defective Interfering; Virus, Defective; Particles, Defective Interfering; Particle, Defective Interfering; Interfering Viruses, Defective; Interfering Virus, Defective; Interfering Particles, Defective; Interfering Particle, Defective; Incomplete Virus; Hybrids, Defective; Hybrid, Defective; Defective Virus; Defective Interfering Virus

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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