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Cytopathogenic Effect, Viral

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Definition: Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysosomal enzymes, changes in cell membrane permeability, diffuse changes in intracellular structures, presence of viral inclusion bodies, and chromosomal aberrations. It excludes malignant transformation, which is CELL TRANSFORMATION, VIRAL. Viral cytopathogenic effects provide a valuable method for identifying and classifying the infecting viruses.  NIM; do not confuse with CELL TRANSFORMATION, VIRAL: see note there; DF: CPE or CPE VIRAL   
See Also Viral Plaque Assay 		Other names Cytopathic Effect, Viral; Viral Cytopathogenic Effects; Viral Cytopathic Effects; Viral Cytopathic Effect; Effects, Viral Cytopathogenic; Effects, Viral Cytopathic; Effect, Viral Cytopathogenic; Effect, Viral Cytopathic; Cytopathogenic Effects, Viral; Cytopathic Effects, Viral; Viral Cytopathogenic Effect

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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