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Chondroitin Lyases

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Definition: Enzymes which catalyze the elimination of delta-4,5-D-glucuronate residues from polysaccharides containing 1,4-beta-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages thereby bringing about depolymerization. EC 4.2.2.4 acts on chondroitin sulfate A and C as well as on dermatan sulfate and slowly on hyaluronate. EC 4.2.2.5 acts on chondroitin sulfate A and C.  do not confuse with CHONDROITIN ABC LYASE   
Examples Chondroitin ABC Lyase 		Other names Chondroitin Sulfate Lyase; Chondroitin Eliminase; Chondroitin B Lyase; Chondroitin AC Lyase; Sulfate Lyase, Chondroitin; Lyases, Chondroitin; Lyase, Chondroitin Sulfate; Lyase, Chondroitin B; Lyase, Chondroitin AC; Eliminase, Chondroitin; Chondroitinase AC II; Chondroitinase-AC II

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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