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Calcium Channel Agonists

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Definition: Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.  vasoconstrictors; DF: CALCIUM CHANNEL AGON or CALCIUM CHANNEL AG    Other names Calcium Channel Agonists, Exogenous; Calcium Channel Activators; Channel Agonists, Calcium; Channel Agonist, Calcium; Channel Activators, Calcium; Agonists, Calcium Channel; Agonist, Calcium Channel; Activators, Calcium Channel; Exogenous Calcium Channel Agonists; Calcium Channel Agonist
Substances having this pharmacologic action: CGP 28392; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcitriol; 1-ethyl-2-benzimidazolinone; adenophostin A; FPL 64176; PN 202-791; SAN 202791

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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