Definition: A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9)
/blood supply /chem /second /secret /ultrastruct permitted; coord IM with SKIN NEOPLASMS (IM)
Other names Disease, Bowen's; Disease, Bowen; Bowens Disease; Bowen Disease
