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Biological Assay

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Definition: A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc.  assays using living-matter intermediate; check text: not all "bioassays" are MeSH term BIOLOGICAL ASSAY; Manual 22.27; DF: BIOL ASSAY   
Examples Limulus Test 		Other names Bioassay; Biological Assays; Assays, Biologic; Assay, Biologic; Biologic Assays; Biologic Assay; Assays, Biological; Assay, Biological; Bioassays

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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