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sitagliptin

under Pyrazines
More information in Books or onNLM PubMed
More on Pyrazines Definition:   do not confuse with PYRIDAZINES   
SubstanceCAS Registry & nameCategoriesSourceDrugs*
sitagliptin [ 4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine,Januvia,MK 0431,MK-0431,MK0431,sitagliptin phosphate ]
  MK-0431 is the phosphate salt of the (2R)-isomer; inhibitor of DPP4 protein resulting in enhanced level of Glucagon-Like Peptide 1; structure in first source 		0   *Pyrazines *Triazoles Glucagon-Like Peptide 1
Pharma Action Dipeptidyl-Peptidase IV Inhibitors 		J Med Chem 2005 Jan 13;48(1):141-51 JUVISYNC; JANUVIA

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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