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tafluprost

under Prostaglandins F
More information in Books or onNLM PubMed
More on Prostaglandins F Definition: (9 alpha,11 alpha,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid (PGF(1 alpha)); (5Z,9 alpha,11,alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid (PGF(2 alpha)); (5Z,9 alpha,11 alpha,13E,15S,17Z)-9,11,15-trihydroxyprosta-5,13,17-trien-1-oic acid (PGF(3 alpha)). A family of prostaglandins that includes three of the six naturally occurring prostaglandins. All naturally occurring PGF have an alpha configuration at the 9-carbon position. They stimulate uterine and bronchial smooth muscle and are often used as oxytocics.  /biosyn /physiol permitted; /chem syn permitted: do not convert to PROSTAGLANDINS F, SYNTHETIC; DF: PGF    Other names PGF; F, Prostaglandins
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tafluprost [ AFP-168,1-methylethyl (5Z)-7-((1R,2R, 3R,5S)-2-((1E)-3,3-difluoro-4-phenoxy -1-butenyl)-3,5-dihydroxycyclopentyl)-5-heptenoate ]
  structure in first source
0   *Prostaglandins F Exp Eye Res. 2004 Apr;78(4):767-76 ZIOPTAN

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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