Definition: Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.
Other names Humanized Antibodies; Antibodies, Humanized
bevacizumab [ Avastin,Genetech brand of bevacizumab ] anti-VEGF monoclonal antibody consisting of humanized murine antibody with antigen-binding, complementary-determining regions from murine VEGF
