encyclopedia of medical concepts
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belotecan

under Camptothecin
More information in Books or onNLM PubMed
More on Camptothecin Definition: An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.      Other names Camptothecine
SubstanceCAS Registry & nameCategoriesSourceDrugs*
belotecan [ 7-(2-(N-isopropylamino)ethyl)camptothecin,CKD 602,CKD-602,CKD602,belotecan hydrochloride ]
  structure in first source 		0   Camptothecin/*analogs & derivatives
Pharma Action Topoisomerase I Inhibitors 		Arch Pharm Res 1998 Oct;21(5):581-90

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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