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caspase-activated DNase inhibitor

under Apoptosis Regulatory Proteins
More information in Books or onNLM PubMed
More on Apoptosis Regulatory Proteins Definition: A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS such as CASPASES.      Other names Regulatory Proteins, Apoptosis; Survival Factors (Apoptosis); Programmed Cell Death Proteins; Death Factors (Apoptosis); Apoptosis Inhibiting Proteins; Apoptosis Inducing Proteins; Pro-Apoptotic Proteins; Anti-Apoptotic Proteins
SubstanceCAS Registry & nameCategoriesSourceDrugs*
caspase-activated DNase inhibitor [ CAD inhibitor,DFF45 protein, human,DFFA protein, human,DNA fragmentation factor 45 protein, mouse,DNA fragmentation factor, 45kDa, alpha polypeptide, human,DNA fragmentation factor, alpha subunit protein, mouse,DNA fragmention factor 45 protein, human,DREP-1 protein, Drosophila,Dff45 protein, mouse,Dffa protein, mouse,Drep1 protein, Drosophila,ICAD (inhibitor),ICAD protein, Drosophila,Rep1 protein, Drosophila,dICAD protein, Drosophila,inhibitor of caspase-activated DNase ]
  from mouse T-lymphoma, with two forms short (S) & long (L); ICAD is the mouse homolog of human DFF45
0   *Apoptosis Regulatory Proteins Deoxyribonucleases/antagonists & inhibitors Apoptosis
Pharma Action Enzyme Inhibitors
Nature 1998 Jan 1;391(6662):43-50

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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