encyclopedia of medical concepts
ψ

Y 27632

under Amides
More information in Books or onNLM PubMed
More on Amides Definition: Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh's Chemical Dictionary, 5th ed)     
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Y 27632 [ N-(4-pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide,Y 27632, (4(R)-trans)-isomer,Y 27632, (4(S)-trans)-isomer,Y 27632, (trans)-isomer,Y 27632, dihydrochloride, (4(R)-trans)-isomer,Y-27632,Y27632 ]
  RN given for di-HCl salt; inhibits Rho-associated protein kinase; inhibits calcium sensitization to affect smooth muscle relaxation; structure in first source
138381-45-0   *Amides *Pyridines
Pharma Action Antihypertensive Agents; Enzyme Inhibitors; Muscle Relaxants, Central
Nature 1997 Oct 30;389(6654):990-4

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify.
We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy