encyclopedia of medical concepts
ψ
N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone
under Amino Acid Chloromethyl Ketones
More information
in Books
or on
More on
Amino Acid Chloromethyl Ketones
Definition
: Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.
serine proteinase inhib; DF: AACK
Other names
Peptide Chloromethyl Ketones; Ketones, Peptide Chloromethyl; Chloromethyl Ketones, Peptide
Substance
CAS Registry & name
Categories
Source
Drugs
*
N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone [ Ac-Tyr-Val-Ala-Asp-CMK,Ac-YVAD-cmk,N-acetyl-tyrosinyl-valinyl-alanyl-aspartyl chloromethyl ketone,N-acetyltyrosinylvalinylalanylaspartylchloromethyl ketone,YVAD-CMK,YVAD-chloromethylketone ]
0
*Amino Acid Chloromethyl Ketones
Pharma Action
Cysteine Proteinase Inhibitors
Biochem J 1996 Feb 15;314(Pt 1):27-32