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imiglucerase

under Glucosylceramidase
More information in Books or onNLM PubMed
More on Glucosylceramidase Definition: A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.  /defic: consider also GAUCHER DISEASE    Other names Glucocerebrosidase; beta-Glucosidase, Glucosylceramide; beta-Glucosidase, Glucocerebroside; beta-Glucosidase, Acid; beta Glucocerebrosidase; Hydrolase, Glucosylsphingosine Glucosyl; Glucosylceramide beta Glucosidase; Glucosyl Hydrolase, Glucosylsphingosine; Glucocerebroside beta Glucosidase; Ceramidase, Glucosyl; Acid beta Glucosidase; beta-Glucocerebrosidase; Glucosylsphingosine Glucosyl Hydrolase; Glucosylceramide beta-Glucosidase; Glucosyl Ceramidase; Glucocerebroside beta-Glucosidase; Acid beta-Glucosidase Drugs: ELELYSO
SubstanceCAS Registry & nameCategoriesSourceDrugs*
imiglucerase [ Cerezyme,Genzyme Brand of Imiglucerase ]
  a mannose-terminated glucocerebrosidase prepared from a recombinant source in Chinese hamster ovary cells 		EC 3.2.1.-   *Glucosylceramidase Gaucher Disease Recombinant Proteins Ann Intern Med 1995 Jan 1;122(1):33-9 CEREZYME

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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