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romidepsin

under Depsipeptides
More information in Books or onNLM PubMed
More on Depsipeptides Definition: Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide linkages. They are commonly cyclized.      Other names Cyclic Depsipeptides; Depsipeptides, Cyclic; Cyclodepsipeptides; Cryptophycins
SubstanceCAS Registry & nameCategoriesSourceDrugs*
romidepsin [ FK228,Astella Pharma Brand of romidepsin,FR 901228,FR-901228,FR901228,istodax ]
  a bicyclic depsipeptide and a potent histone deacetylase inhibitor from Chromobacterium violaceum; structure in first source 		128517-07-7 L-Valine, N-(3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-, xi-lactone, cyclic (1-2)-disulfide, (S-(E))  *Depsipeptides
Pharma Action Antibiotics, Antineoplastic 		J Antibiot (Tokyo) 1994 Mar;47(3):301-10 ISTODAX

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