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abciximab

under Antibodies, Monoclonal
More information in Books or onNLM PubMed
More on Antibodies, Monoclonal Definition: Antibodies produced by a single clone of cells.  do not coordinate with ANTIBODY FORMATION for biosyn; ANTIBODY-TOXIN CONJUGATES is available as a toxin carrier: see note there    Other names Monoclonal Antibodies
SubstanceCAS Registry & nameCategoriesSourceDrugs*
abciximab [ Clotinab,ReoPro,CentoRx,Eli Lilly brand of abciximab,Lilly brand of abciximab,c7E3 Fab,chimeric 7E3 Fab ]
  a monoclonal antibody Fab fragment that blocks the platelet glycoprotein IIb/IIIa receptor & potently inhibits platelet aggregation; used in treatment of refractory unstable angina
143653-53-6   *Antibodies, Monoclonal *Immunoglobulin Fab Fragments Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors
Pharma Action Anticoagulants; Platelet Aggregation Inhibitors
Circulation 1994 Feb;89(2):596-603 REOPRO

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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