encyclopedia of medical concepts
ψ
ψ
GEM91
under Thionucleotides
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Thionucleotides
Definition
: Nucleotides in which the base moiety is substituted with one or more sulfur atoms.
Substance
CAS Registry & name
Categories
Source
Drugs
*
GEM91 [ GEM 91,gene expression modulator 91,trecovirsen ]
a 25-mer antisense oligonucleotide phosphorothioate used as a therapeutic agents for AIDS; may block the translation of gag mRNA& disrupt the secondary structure of RNA
0
*Thionucleotides
Pharma Action
Anti-HIV Agents
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Oligodeoxyribonucleotides, Antisense
Antisense Res Dev 1992 Winter;2(4):261-6