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cimadronate

under Diphosphonates
More information in Books or onNLM PubMed
More on Diphosphonates Definition: Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.      Other names Bisphosphonates
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cimadronate [ YM 175,YM175,YM-175,cycloheptylaminomethylene-1,1-bisphosphonate,hydronium (cycloheptylammonio)methylene-1,1-bisphosphonate,hydronium incadronate,incadronate ]
  increases serum 1,25-dihydroxyvitamin D in rats via stimulating renal 1-hydroxylase activity; structure given in first source
138330-18-4 Phosphonic acid, ((cycloheptylamino)methylene)bis-, disodium salt  *Diphosphonates
Pharma Action Bone Density Conservation Agents
Biochem Biophys Res Commun 1991;180(3):1172

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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