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salivary plasminogen activator alpha 1, Desmodus rotundus

under Plasminogen Activators
More information in Books or onNLM PubMed
More on Plasminogen Activators Definition: A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.  /antag: consider also PLASMINOGEN INACTIVATORS    Other names Uterine Tissue Plasminogen Activator; Uterine-Tissue Plasminogen Activator; Plasminogen Activator; Extrinsic Plasminogen Activators
SubstanceCAS Registry & nameCategoriesSourceDrugs*
salivary plasminogen activator alpha 1, Desmodus rotundus [ DSPA alpha 1 protein, Desmodus rotundus,Desmodus salivary plasminogen activator,desmoteplase,salivary plasminogen activator, vampire bat ]
  displays strict fibrin specificity; cleared fourfold slower from circulation than t-PA
0   *Plasminogen Activators Recombinant Proteins
Pharma Action Fibrinolytic Agents
Circulation 1991;84(1):244

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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