Definition: A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
Other names RU486; ZK 98296; RU38486; RU 486; RU 38486; R 38486; Mifepristone Exelgyn Brand; Mifepristone Danco Brand; Mifepristone Contragest Brand; ZK98296; ZK-98296; RU-486; RU-38486; R38486; R-38486; Mif+¬gyne; Mifeprex; Mifegyne; Exelgyn Brand of Mifepristone; Danco Brand of Mifepristone