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ICI 198583

under Folic Acid
More information in Books or onNLM PubMed
More on Folic Acid Definition: A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.      Other names Vitamin M; Pteroylglutamic Acid; B9, Vitamin; Vitamin B9; Folvite; Folic Acid, Potassium Salt; Folic Acid, Monosodium Salt; Folic Acid, Sodium Salt; Folic Acid, Monopotassium Salt; Folic Acid, Calcium Salt (1:1); Folic Acid, (DL)-Isomer; Folic Acid, (D)-Isomer; Folate; Folacin Drugs: FOLICETFOLIC ACID; FOLVITE;
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ICI 198583 [ 2-deamino-PDDF,2-desamino-2-methyl-N(10)-propargyl-5,8-dideazafolic acid,ICI-198583,ICI198583 ]
  RN & structure given in first source 		112887-62-4   Folic Acid/*analogs & derivatives Thymidylate Synthase/antagonists & inhibitors
Pharma Action Antineoplastic Agents; Enzyme Inhibitors; Folic Acid Antagonists 		J Med Chem 1989;32(6):1284

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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