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jasplakinolide

under Depsipeptides
More information in Books or onNLM PubMed
More on Depsipeptides Definition: Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide linkages. They are commonly cyclized.      Other names Cyclic Depsipeptides; Depsipeptides, Cyclic; Cyclodepsipeptides; Cryptophycins
SubstanceCAS Registry & nameCategoriesSourceDrugs*
jasplakinolide [ NSC 613009,jaspamide ]
  cyclodepsipeptide isolated from marine sponge Jaspis; active against Candida; RN refers to 2S-(2R*,4E,6S*,8R*)-isomer; structure in first source
102396-24-7   *Depsipeptides
Pharma Action Antifungal Agents; Antineoplastic Agents; Insecticides
Antimicrob Agents Chemother 1988;32(8):1154

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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