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jasplakinolide
under Depsipeptides
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Depsipeptides
Definition
: Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide linkages. They are commonly cyclized.
Other names
Cyclic Depsipeptides; Depsipeptides, Cyclic; Cyclodepsipeptides; Cryptophycins
Substance
CAS Registry & name
Categories
Source
Drugs
*
jasplakinolide [ NSC 613009,jaspamide ]
cyclodepsipeptide isolated from marine sponge Jaspis; active against Candida; RN refers to 2S-(2R*,4E,6S*,8R*)-isomer; structure in first source
102396-24-7
*Depsipeptides
Pharma Action
Antifungal Agents
;
Antineoplastic Agents
;
Insecticides
Antimicrob Agents Chemother 1988;32(8):1154