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tirilazad

under Pregnatrienes
More information in Books or onNLM PubMed
More on Pregnatrienes Definition: Pregnane derivatives containing three double bonds in the ring structures.     
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tirilazad [ 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)-triene-3,20-dione monomethane sulfonate,Freedox,Pharmacia brand of tirilazad mesylate hydrate,U 74006F,U-74006,U-74006F,U74006F,tirilazad mesylate,tirilazad mesylate hydrate ]
  a lazaroid; potent inhibitor of iron-dependent lipid peroxidation; has shown excellent activity in in vivo models of experimental central nervous system trauma & ischemia; structure given in first sou 		110101-67-2 Pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methyl-, (16alpha)-, monomethanesulfonate  *Pregnatrienes
Pharma Action Antioxidants; Neuroprotective Agents 		J Biol Chem 1987;262(22):10438

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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