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ONO 3708

under Thromboxane A2
More information in Books or onNLM PubMed
More on Thromboxane A2 Definition: An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).  /biosyn /physiol permitted    Other names Rabbit Aorta Contracting Substance; A2, Thromboxane
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ONO 3708 [ (9,11)(11,12)-dideoxa-9 alpha,11 alpha-dimethylmethano-11,12-methano-13,14-dihydro-13-aza-14-oxo-15-cyclopentyl-16,17,18,19,20-pentanor-15-epi-TXA2,(9,11),(11,12)-dideoxa-9,11-dimethylmethano-11,12-methano-13,14-dihydro-13-azo-14-oxo-15-cyclopentyl-16,17,18,19,20-pentanor-15-epithromboxane A2,ONO-3708 ]
  structure given in first source; thromboxane A2 antagonist 		102191-05-9 5-Heptenoic acid, 7-(3-((cyclopentylhydroxyacetyl)amino)-6,6-dimethylbicyclo(3.1.1)hept-2-yl)-, (1S-(1alpha,2beta(Z),3alpha(S*),5alpha))  Thromboxane A2/*analogs & derivatives
Pharma Action Platelet Aggregation Inhibitors 		J Cardiovasc Pharmacol 1986;8(4):818

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