encyclopedia of medical concepts
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mafosfamide

under Cyclophosphamide
More information in Books or onNLM PubMed
More on Cyclophosphamide Definition: Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.      Other names Monohydrate, Cyclophosphamide; Sendoxan; Procytox; Neosar; NSC-26271; Endoxan; Cytoxan; Cytophosphan; Cyclophosphane; Cyclophosphamide, (S)-Isomer; Cyclophosphamide, (R)-Isomer; Cyclophosphamide, (+-)-Isomer; Cyclophosphamide Monohydrate; B-518 Drugs: LYOPHILIZED CYTOXANNEOSAR; CYTOXAN; CYCLOPHOSPHAMIDE;
SubstanceCAS Registry & nameCategoriesSourceDrugs*
mafosfamide [ 2-((2-(bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorin-4-yl)thio)ethanesulfonic acid P-oxide,z 7557,z-7557 ]
  RN given refers to cis-(+-)-isomer
88859-04-5   Cyclophosphamide/*analogs & derivatives
Pharma Action Adjuvants, Immunologic; Antineoplastic Agents
Cancer Res 1986;46(5):2214

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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