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1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol

under Misonidazole
More information in Books or onNLM PubMed
More on Misonidazole Definition: A nitroimidazole that sensitizes normally radio-resistant hypoxic cells to radiation. It may also be directly cytotoxic to hypoxic cells and has been proposed as an antineoplastic.      Other names Ro 70582; Ro 7 0582; Ro 070582; Ro 07 0582; alpha-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethan; Ro 7-0582; Ro 07-0582
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol [ NSC 347503,NSC-347503,RSU 1069,RSU-1069 ]
  structure given in first source
88876-88-4 1H-Imidazole-1-ethanol, alpha-(1-aziridinylmethyl)-2-nitro  Misonidazole/*analogs & derivatives
Pharma Action Antineoplastic Agents; Radiation-Sensitizing Agents
Br J Cancer 1984;49(5):571

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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