Definition: Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).
Sch 28080 [ 2-methyl-8-(phenylmethoxy)imidazo-(1-2-a)pyrine-3-acetonitrile,S28080,Sch-28080,Sch28080,Schering compound 28080 ] not related structurally to other known anti-ulcer agents; inhibits histamine-stimulated gastric secretion; prevents gastric lesions induced by aspirin, indomethacin & ethanol