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MSH, 4-Nle-7-Phe-alpha-

under alpha-MSH
More information in Books or onNLM PubMed
More on alpha-MSH Definition: A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.      Other names alpha-Melanocyte-Stimulating Hormone; MSH, alpha; alpha-Melanocyte-Stimulating Hormone, Desacetyl; alpha-MSH, Desacetyl; alpha Melanotropin; alpha Melanocyte Stimulating Hormone; alpha MSH; MSH, Des-Acetyl; Hormone, alpha-Melanocyte-Stimulating; Hormone, Desacetyl alpha-Melanocyte-Stimulating; Desacetyl alpha Melanocyte Stimulating Hormone; Desacetyl alpha MSH; alpha-Melanotropin; MSH, (Desacetyl)alpha; Desacetyl alpha-Melanocyte-Stimulating Hormone; Desacetyl alpha-MSH; Des-Acetyl MSH; DE-alpha-MSH; Adrenocorticotropin (1-13)NH2; Acetylated ACTH (1-13)NH2
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MSH, 4-Nle-7-Phe-alpha- [ NDPMSH,(Nle(4),D-Phe(7))alpha-MSH,(Nle(4)-DPhe(7))alpha-melanocyte-stimulating hormone,4-Nle-7-Phe-alpha-MSH,4-norleucine-7-D-phenylalanine-alpha-melanocyte-stimulating hormone,4-norleucyl-7-phenylalanine-alpha-MSH,MSH, 4-norleucyl-7-phenylalanine-alpha-,MT-1 (NleFMSH),Melanotan-1,NDP-MSH,alpha-MSH, Nle(4)-Phe(7)-,alpha-MSH, norleucyl(4)-D-phenylalanyl(7)- ] 75921-69-6 alpha-Melanotropin, 4-L-norleucine-7-D-phenylalanine  alpha-MSH/*analogs & derivatives
Pharma Action Affinity Labels; Anticarcinogenic Agents 		Proc Natl Acad Sci USA 1980;77(1):5754

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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