Definition: Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
a blood coag factor: do not confuse X ref FACTOR I with COMPLEMENT FACTOR I
Other names Factor I; Coagulation Factor I; gamma Fibrinogen; I, Coagulation Factor; Factor I, Coagulation; gamma-Fibrinogen; Blood Coagulation Factor I
