Definition: A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.
1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine [ 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine, (R)-isomer,C18-PAF,octadecyl PAF,octadecyl-AGPC,octadecyl-PAF-acether ] reported to have same biological activity as natural PAF-acether; RN given refers to parent cpd without isomeric designation